This phrase is used to express that you don't like someone or something, or that you do not feel comfortable with a particular person or situation. It literally translates to 'He/She/It is not a saint of my devotion'.
Examples
- Spanish: 'No me inviten a la fiesta de Pedro. Ese no es santo de mi devoción'.
- English: 'Don't invite me to Pedro's party. He is not a saint of my devotion' or in more natural English, 'Don't invite me to Pedro's party. I don't really like him'.